Tomoyuki Furubayashi - My portal

Profile Information

Affiliation: Assistant Professor, School of Pharmacy, Department of Pharmaceutical Sciences, Shujitsu University

Degree: Master(Pharmaceutics)(Graduate School of Setsunan University)
PhD(Okayama University)

J-GLOBAL ID: 200901040049605722
researchmap Member ID: 5000084730

Research Interests

Research Areas

Life sciences / Clinical pharmacy /

Research History

2008 - Present

School of Pharmacy, Shujitsu University
2007 - 2008

School of Pharmacy, Shujitsu University
2003 - 2008

Research Associate, School of Pharmacy,
2008

- Assistant professor, School of Pharmacy,
2003 - 2006

School of Pharmacy, Shujitsu University
2002 - 2003

科学技術振興事業団研究成果活用プラザ石川
2002 - 2003

Researcher, Project of the Development
1997 - 2002

東光薬品工業株式会社研究開発部研究員
1997 - 2002

Researcher, Toko Pharmaceutical Industry,
「軟骨再生用超分子スキャフォールドの開発プロジェクト」研究員
Shujitsu University
Regeneration, Innovation Plaza Ishikawa, JST
of Supramolecular Scaffold for Cartilage
Development of Research and Development

Education

Misc.

Transnasal Delivery of Methotrexate to Brain Tumors in Rats: A New Strategy for Brain Tumor Chemotherapy

Tomotaka Shingaki, Daisuke Inoue, Tomoyuki Furubayashi, Toshiyasu Sakane, Hidemasa Katsumi, Akira Yamamoto, Shinji Yamashita

MOLECULAR PHARMACEUTICS, 7(5) 1561-1568, Sep, 2010
The transnasal delivery of 5-fluorouracil to the rat brain is enhanced by acetazolamide (the inhibitor of the secretion of cerebrospinal fluid)

Tomotaka Shingaki, Ismael J. Hidalgo, Tomoyuki Furubayashi, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto, Shinji Yamashita

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 377(1-2) 85-91, Jul, 2009
The transnasal delivery of 5-fluorouracil to the rat brain is enhanced by acetazolamide (the inhibitor of the secretion of cerebrospinal fluid)

Tomotaka Shingaki, Ismael J. Hidalgo, Tomoyuki Furubayashi, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto, Shinji Yamashita

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 377(1-2) 85-91, Jul, 2009
Kinetic model to predict the absorption of nasally applied drugs from in vitro transcellular permeability of drugs

Tornoyuki Furubayashi, Akiko Kamaguchi, Kazushi Kawaharada, Yoshie Masaoka, Makoto Kataoka, Shinji Yamashita, Yutaka Higashi, Toshiyasu Sakane

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 30(5) 1007-1010, May, 2007
Kinetic model to predict the absorption of nasally applied drugs from in vitro transcellular permeability of drugs

Tornoyuki Furubayashi, Akiko Kamaguchi, Kazushi Kawaharada, Yoshie Masaoka, Makoto Kataoka, Shinji Yamashita, Yutaka Higashi, Toshiyasu Sakane

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 30(5) 1007-1010, May, 2007
Evaluation of the contribution of the nasal cavity and gastrointestinal tract to drug absorption following nasal application to rats

Tomoyuki Furubayashi, Akiko Kamaguchi, Kazushi Kawaharada, Yoshie Masaoka, Makoto Kataoka, Shinji Yamashita, Yutaka Higashi, Toshiyasu Sakane

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 30(3) 608-611, Mar, 2007
Evaluation of the contribution of the nasal cavity and gastrointestinal tract to drug absorption following nasal application to rats

Tomoyuki Furubayashi, Akiko Kamaguchi, Kazushi Kawaharada, Yoshie Masaoka, Makoto Kataoka, Shinji Yamashita, Yutaka Higashi, Toshiyasu Sakane

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 30(3) 608-611, Mar, 2007
Influence of formulation viscosity on drug absorption following nasal application in rats

Tomoyuki Furubayashi, Daisuke Inoue, Akiko Kamaguchi, Yutaka Higashi, Toshiyasu Sakane

DRUG METABOLISM AND PHARMACOKINETICS, 22(3) 206-211, 2007
Influence of formulation viscosity on drug absorption following nasal application in rats

Tomoyuki Furubayashi, Daisuke Inoue, Akiko Kamaguchi, Yutaka Higashi, Toshiyasu Sakane

DRUG METABOLISM AND PHARMACOKINETICS, 22(3) 206-211, 2007
Novel Biodegradable Cholesterol-Introduced Polyrotaxane Hydrogels for Cartilage Regeneration

W. Tachaboonyakiat, T. Furubayashi, M. Katoh, T. Ooya, N. Yui

J. Biomater. Sci. Polym. Ed., 15(11) 1389-1404, 2004
Novel biodegradable cholesterol-modified polyrotaxane hydrogels for cartilage regeneration

W Tachaboonyakiat, T Furubayashi, M Katoh, T Ooya, N Yui

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 15(11) 1389-1404, 2004
DEVELOPMENT OF NASAL DOSAGE FORM OF OXATOMIDE FOR RHINITIS

Furubayashi Tomoyuki, Kobayashi Yoichi, Yamashita Shinji, Sakane Toshiyasu, Kawauchi Hideyuki

Japanese Journal of Allergology, 52(10) 992-998, 2003
Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells

S Yamashita, T Furubayashi, M Kataoka, T Sakane, H Sezaki, H Tokuda

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 10(3) 195-204, May, 2000
Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells.

Yamashita, S, Furubayashi, T, Kataoka, M, Sakane, T, Sezaki, H, Tokuda, H

Eur. J. Pharm. Sci., 10(3) 195-204, 2000

Presentations

薬物の経鼻吸収性評価システムの開発とその有用性

第26回日本DDS学会, 2010
鼻腔内適用型粉末医薬品のin vivo吸収性評価システムの開発Ⅱ

日本薬剤学会第25年会, 2010
EVALUATION SYSTEM ON IN VIVO NASAL ABSORPTION OF DRUG FROM DRY POWDER FORMULATIONS

第26回日本薬物動態学会年会, 2009
DEVELOPMENT OF IN VITRO EVALUATION SYSTEMS ON NASAL MUCOCILIARY FUNCTION AND RELATIONSHIP BETWEEN MUCOCILIARY FUNCTION AND NASAL DRUG ABSORPTION

第26回日本薬物動態学会年会, 2009
Evaluation on the in vivo nasal absorption of the drug from a dry powder formulation

2009 AAPS Annual Meeting and Exposition, 2009
Development and characterization of an in vitro evaluation system on the ciliary beat frequency of the rat nasal septum ~ Correlation between mucociliary clearance and ciliary beat frequency ~

2009 AAPS Annual Meeting and Exposition, 2009
Establishment of kinetic model for estimating the drug absorption from viscous formulation following nasal application

2009 AAPS Annual Meeting and Exposition, 2009
薬物の経鼻吸収性評価システムの開発～粘性製剤からの薬物吸収性評価～

第25回日本DDS学会, 2009
鼻腔内投与後の薬物吸収と繊毛運動（MC)との関係Ⅲ－MCの変動に対する薬物及び製剤添加物の影響－

日本薬学会第129年会, 2009
Establishment and characterization of an in vitro evaluation system on the nasal mucociliary clearance

2008 AAPS Annual Meeting and Exposition, 2008
Influence of formulation viscosity on drug absorption following nasal application in rats

2008 AAPS Annual Meeting and Exposition, 2008
薬物の経鼻吸収性に及ぼす製剤粘性の影響とCaco-2単層膜による評価

第47回日本薬学会中国四国支部学術大会, 2008
INFLUENCE OF FORMULATION VISCOSITY ON THE NASAL DRUG ABSORPTION IN RATS

第25回日本薬物動態学会年会, 2008
光に不安定な薬剤の簡易懸濁法における安定性の検討

第18回日本医療薬学会年会, 2008
ラット鼻腔内繊毛運動評価におけるmucociliary clearanceの機能維持と部位差に関する検討

日本薬剤学会第23年会, 2008
薬物の経鼻吸収に及ぼす製剤粘性の影響とその評価

日本薬剤学会第23年会, 2008
Establishment and characterization of an in vitro evaluation system on the nasal mucociliary clearance

2008 AAPS Annual Meeting and Exposition, 2008
Influence of formulation viscosity on drug absorption following nasal application in rats

2008 AAPS Annual Meeting and Exposition, 2008

Professional Memberships

Research Projects

薬物の経鼻吸収メカニズムの解明とリンパ移行性の最適化に関する研究

科学研究費補助金, 2009
薬物の経鼻吸収動態の解明

2008
薬物経鼻吸収性評価システムの開発

2003 - 2007
The development of evaluation and estimation system for in vivo drug absorption following nasal application.

2003 - 2007

Industrial Property Rights

ポリロタキサンとそのヒドロゲル並びに組織再生用基材と軟骨細胞の培養方法