2021年4月15日
Rnd2 differentially regulates oligodendrocyte myelination at different developmental periods
Molecular Biology of the Cell
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- 巻
- 32
- 号
- 8
- 開始ページ
- 769
- 終了ページ
- 787
- 記述言語
- 掲載種別
- 研究論文（学術雑誌）
- DOI
- 10.1091/mbc.e20-05-0332
- 出版者・発行元
- American Society for Cell Biology (ASCB)
The unique biphasic role of Rnd2, an atypical branch of the Rho family GTPases, in oligodendrocyte myelination is described. Rnd2 positively regulates myelination in the early myelinating period and negatively regulates it in the subsequent period, by changes of the Rho-kinase activities, a common downstream molecule of Rho GTPases.
- リンク情報
- ID情報
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- DOI : 10.1091/mbc.e20-05-0332
- ISSN : 1059-1524
- eISSN : 1939-4586
- PubMed ID : 33596091
- PubMed Central 記事ID : PMC8108512