Percutaneous vertebroplasty is a radiologically guided therapeutic procedure that consists of percutaneous injection of polymethylmetacrylate (PMMA) into pathologic vertebral bodies. It is a minimally invasive procedure that is effective in the treatment of pain resulting from bone metastasis. This procedure has the advantage of providing rapid pain relief and spinal stabilization. A patient with severe, aggressive pain from metastatic lumbar spinal tumor of thyroid follicular carcinoma is presented herein. Despite treatment with analgesic agents, external beam radiation therapy, radioiodine therapy, and posterior fusion surgery, the pain reemerged and progressed. After percutaneous vertebroplasty, definite pain relief was achieved. Vertebroplasty would be useful as an additional or alternative pain relief method in patients with metastatic vertebral tumors.経皮的椎体形成術はX線またはCT透視下に病的椎体にpolymethylmetacrylate(PMMA)を注入する治療法である.転移性脊椎腫瘍について,本治療法により迅速かつ侵襲少なく十分な除痛効果と脊椎の安定化が得られる.甲状腺濾胞癌の腰椎転移による難治性痙痛に対して本治療が有効であった1例を報告する.腰椎転移に対して放射性ヨード内服治療,放射線外照射,脊椎固定術および鎮痛剤内服など様々な治療を行うも痺痛が再出現,増悪したが本治療を行い十分なr痛緩和が得られた.経皮的椎体形成術は転移性椎体腫瘍による難治性疼痛に対する追加治療または代替治療として有用であると考えられた.