Kajimura Mayumi
(梶村 眞弓)
Modified on: 04/08
Profile Information
- Affiliation
- Visiting Professor, Research Organization for Nano & Life Innovation, Waseda University
- Degree
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Doctor of Philosophy in Physiology(University of California, Davis)
- ORCID ID
- https://orcid.org/0000-0003-3773-6874
- J-GLOBAL ID
- 200901057291116701
- researchmap Member ID
- 1000314936
My research focuses on how various gaseous molecules such as molecular hydrogen (H2), molecular oxygen (O2), NO, H2S, CO2 and CO are sensed in our body. We are particularly interested in the interaction between gaseous molecules and their receptor proteins, gas-sensing proteins and how these gaseous molecules modulate vascular tone in various organs. While the NO signaling has been well-defined, the CO signaling requires further investigation with respect to identifying receptor molecules and their downstream effectors. Like NO, CO has an ability to bind to the ferrous heme of a variety of proteins with high affinity; thus, it is capable of either stimulating or inhibiting catalytic activities of heme proteins. Thus in current studies we are investigating the possibility that CO targets for proteins containing prosthetic heme and by altering their activity it controls the CNS function. We use both in vivo and in vitro systems in parallel to compensate inherent weakness of each model. This requires developing techniques which range from molecular biology, cell biology, protein biochemistry, and single vessel studies to whole animals.
Research Interests
5Research Areas
5Research History
11-
Oct, 2022 - Apr, 2024
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Apr, 2016 - Mar, 2022
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Oct, 2012 - Mar, 2016
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Jan, 2009 - Sep, 2012
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Oct, 2006 - Dec, 2008
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Dec, 1999 - Sep, 2006
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Oct, 1999 - Nov, 1999
Education
1Committee Memberships
20-
Oct, 2019 - Sep, 2021
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Apr, 2019 - Sep, 2021
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Oct, 2017 - Sep, 2021
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Oct, 2017 - Sep, 2021
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Dec, 2018 - Nov, 2020
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Apr, 2020 - Oct, 2020
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Feb, 2010 - Feb, 2020
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Dec, 2017 - Nov, 2018
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Dec, 2016 - Nov, 2017
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Mar, 2017 - Sep, 2017
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Oct, 2016 - Sep, 2017
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Aug, 2015 - Jul, 2017
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Aug, 2015 - Jul, 2017
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Aug, 2014 - Jul, 2016
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Oct, 2012 - Mar, 2016
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Aug, 2013 - Oct, 2015
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Apr, 2011 - Sep, 2015
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Oct, 2011 - Sep, 2015
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Apr, 2009 - Mar, 2015
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Apr, 2009 - Mar, 2014
Awards
9-
Jun, 2022
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Jun, 2021
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Jun, 2020
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Jul, 2019
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Jun, 2017
Papers
89-
Shock, Publish Ahead of Print(3) 377-385, Oct 17, 2019 Peer-reviewed
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脳循環代謝, 30(1) 143-143, Oct, 2018
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Nuclear Medicine and Biology, 56 26-30, Jan 1, 2018 Peer-reviewed
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ASN Neuro, 10 1-12, 2018 Peer-reviewed
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Journal of Clinical Biochemistry and Nutrition, 63(1) 70-79, 2018
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EJNMMI RESEARCH, 7(1) 19, Feb, 2017 Peer-reviewed
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ELIFE, 5, Nov, 2016 Peer-reviewed
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Free radical biology & medicine, 99 333-344, Oct, 2016 Peer-reviewed
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Journal of the Neurological Sciences, 368 326-333, Sep 15, 2016
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JOURNAL OF THE NEUROLOGICAL SCIENCES, 368 326-333, Sep, 2016 Peer-reviewed
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Scientific reports, 6 32361-32361, Sep 1, 2016 Peer-reviewed
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JSBMS Letters, 41(Suppl.) 48-48, Aug, 2016
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日本抗加齢医学会総会プログラム・抄録集, 16回 129-129, Jun, 2016
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ACTA NEUROCHIRURGICA, 158(6) 1057-1067, Jun, 2016 Peer-reviewed
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Acta Neurochirurgica, 158(6) 1057-1067, Jun 1, 2016 Peer-reviewed
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JOURNAL OF NEUROINFLAMMATION, 13(1) 99, May, 2016 Peer-reviewed
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Microcirculation, 23(3) 183-90, Apr, 2016
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日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 88回・38回 [1W7-5], Dec, 2015
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Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(5) 794-805, May, 2015
Misc.
38-
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 37 401-401, Apr, 2017
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JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 36 354-355, Jun, 2016
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JOURNAL OF INVESTIGATIVE DERMATOLOGY, 136(5) S60-S60, May, 2016
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MICROCIRCULATION, 23(3) 183-190, Apr, 2016
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JOURNAL OF PHARMACOLOGICAL SCIENCES, 124 41P-41P, 2014
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酸化ストレスの医学, 137-144, 2014
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がんと代謝研究会プログラム&抄録集, 1st, 2013
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RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 184(2) 139-148, Nov, 2012
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FREE RADICAL BIOLOGY AND MEDICINE, 53 S60-S61, Sep, 2012
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JOURNAL OF MOLECULAR MEDICINE-JMM, 90(3) 245-254, Mar, 2012
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実験医学 増刊, 30(2) 90-97, 2012
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International review of thrombosis, 6(4) 358-361,298-299, Dec, 2011
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日本NO学会学術集会プログラム抄録集, 11th, 2011
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JOURNAL OF VASCULAR RESEARCH, 48 184-184, 2011
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細胞工学, 30(1) 10-19, 2011
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NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 22 S31-S32, Jun, 2010
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日本薬学会年会要旨集, 130th(3) 226-226, Mar 5, 2010
Presentations
6-
World Congress of Internal Medicine, May, 2002
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第72回日本生化学学会大会 (2001), Nov, 2001
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第26回日本微小循環学会, Feb, 2001
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日本組織細胞化学会シンポジウム「活性酸素の視覚化」, Dec, 2000
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第73回日本生化学会, Oct, 2000
Major Teaching Experience
21-
Apr, 2018 - Mar, 2022
Professional Memberships
3Research Projects
18-
Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), MEXT,JSPS, Apr, 2019 - Mar, 2022
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Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), MEXT,JSPS, Apr, 2016 - Mar, 2019
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委託研究費, 島津製作所, Apr, 2015 - Mar, 2017
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Jun, 2015 - May, 2016
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Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2016
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The Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency,, Jul, 2015 - Mar, 2016
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The Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Agency, Apr, 2015 - Mar, 2016
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Grant-in-Aid for Scientific Research, • Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015
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Grant-in-Aid for Scientific Research, 日本学術振興会, Apr, 2009 - Mar, 2012
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教育研究高度化のための支援体制整備事業, 教育研究高度化のための支援体制整備事業, Apr, 2009 - Mar, 2010
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Health and Labour Sciences Research Grants, Apr, 2008 - Mar, 2009
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Grant-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2007 - Mar, 2009
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Health and Labour Sciences Research Grants, Apr, 2007 - Mar, 2008
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Health and Labour Sciences Research Grants, 厚生労働省, Apr, 2006 - Mar, 2007
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Grant-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2005 - Mar, 2007
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Health and Labour Sciences Research Grants, Apr, 2005 - Mar, 2006
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Grant-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2003 - Mar, 2005
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Grant-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Apr, 2001 - Mar, 2003