Profile Information

Affiliation
-
客員教授, 生理学研究所
客員教授, 滋賀医科大学
Degree
医学博士
J-GLOBAL ID
201101091683166245
researchmap Member ID
B000001749
一貫してパーキンソン病(PD)とALSの分子メカニズム解明とそれに基づく治療法開発をめざして研究を行っている。家族性PDでは多くの病因遺伝子が見出されているにもかかわらず、適切な遺伝子改変動物が得られていないという問題点が病態および治療研究の進展を阻んでいる。我々は最近魚類であるメダカで家族性PDモデルの作製に取り組んでおり、興味深い知見が得られつつある。ALSに関してはタンパク質分解系の破綻による孤発性ALSモデルの作製に取り組むほか、病因遺伝子発現を転写レベルで抑制する治療法の開発に力を注いでいる。またPDについてはiPS細胞研究所との共同研究で疾患特異的iPS細胞の樹立と解析にも取り組んでいる。

Research Interests

  34

Research Areas

  4

Research History

  14

Papers

  1076
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Misc.

  853
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Research Projects

  54
  • 戦略的な研究開発の推進 ムーンショット型研究開発事業, 科学技術振興機構, 2020 - 2025
    高橋 良輔
  • 科学研究費助成事業, 基盤研究(A), 日本学術振興会, Apr, 2021 - Mar, 2024
    高橋 良輔
  • Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021
    Takahashi Ryosuke
  • 科学研究費助成事業 新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2017 - Mar, 2019
    高橋 良輔
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2018
    Nagami Shinsuke, Oku Yoshitaka, Yagi Naomi, Takahashi Ryosuke, Kayashita Jun, Yamagata Yoshie
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2018
    Hatanaka Yusuke, TAKAHASHI Ryosuke
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2018
    Uemura Maiko, TAKAHASHI Ryosuke, UEMURA Norihito, OKUDA Shinya, TAGUCHI Tomoyuki, TAMANO Ryotaro
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018
    Takahashi Ryosuke, YAMAKADO Hodaka, UEMURA Norihito, Ikuno Masashi, Nakanishi Etsuro
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018
    Ito Hidefumi, ISHIGUCHI Hiroshi, KAWAKAMI Hideshi, TAKAHASHI Ryosuke, INOUE Haruhisa
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2018
    YAMANAKA Koji, Suzumura Akio, Takeuchi Hideyuki, Takahashi Ryosuke, Yamashita Hirofumi, Endo Fumito, Watanabe Seiji
  • 科学研究費助成事業 新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2016 - Mar, 2017
    高橋 良輔
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2016
    Takahashi Ryosuke, UEMURA Norihito
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2016
    Mitsui Takao, MAKI YUKIKO, KAWAMURA KAZUYUKI, KAJI RYUJI, TAKAHASHI RYOSUKE, FUJIMOTO MIKI, SOGO MASAKO
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2016
    Ito Hidefumi, KAWAMOTO YASUHIRO, KAWAKAMI HIDESHI, RYOSUKE TAKAHASHI
  • Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2016
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2016
    Takahashi Ryosuke, Urushitani Makoto
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (S), Grant-in-Aid for Scientific Research (S), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2016
    Takeda Shunichi, HIROTA Kouji, YAMADA Ryo, OKADA Tetsuya, SASANUMA Hiroyuki, SHIMIZU Hiroyasu, TAKAHASHI Ryosuke
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2016
    Takahashi Ryosuke, Kiyama Hiroshi, Yamanaka Koji, Higuchi Makoto, Uchiyama Yasuo, Hattori Nobutaka, Takumi Toru, Kawakami Hideshi, Urushitani Makoto
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2010 - Mar, 2016
    Kimura Minoru, Tanji Jun, Takada Masahiko, Nakamura Katsuki, Ohtsuka Toshihisa, Aoki Shigeki, Takao Hidemasa, Shimoji Keigo, Goto Masami, Yoshiura Takashi, Nakata Yasuhiro, Abe Osamu, Masumoto Tomohiko, Tokumaru Aya, Matsumura Akira, Kirino Eiji, Terada Hitoshi, Sato Noriko, Kasai Kiyoto, Hashimoto Ryota, Niwa Shin-ichi, Kato Tadafumi, Suzuki Michio, Shuji Iritani, Nemoto Kiyotaka, Tomita Hiroaki, Murayama Shigeo, Akatsu Hiroyasu, Takao Masaki, Saito Yuko, Bito Haruhiko, Yoshimura Yumiko, Matsuzaki Masanori, Furuta Toshiaki, Okado Haruo, Saito Izumu, Kaibuchi Kozo, Hasegawa Masato, Aiba Atsu, Shiina Nobuyuki, Igarashi Michihiro, Tomoki Nishioka, Watanabe Masahiko, Koike Masato, Sakagami Hiroyuki, Shigemoto Ryuichi, Fukazawa Yugo, Sakimura Kenji, Mori Hisashi, Mishina Masayoshi, Kobayashi Kazuto, Yanagawa Yuchio, Uemura Tadashi, Ishihara Takeshi, Nose Akinao, Iino Yuichi, Miyakawa Tsuyoshi, Takao Keizo, Mushiake Hajime, Katayama Norihiro, Tanaka Tetsu, Inoue Kazuhide, Okabe Shigeo, Kano Masanobu, Fujiyama Fumino, Isa Tadashi, Kageyama Ryoichiro, Fujita Ichiro, Yoshida Akira, Nishikawa Toru, Nukina Nobuyuki, Fukai Tomoki, Iwatsubo Takeshi, Yamamori Tetsuo, Okazawa Hitoshi, Tanaka Keiji, Kakigi Ryusuke, Tsuda Ichiro, Kitazawa Shigeru, Doya Kenji, Takahashi Ryosuke, Ikenaka Kazuhiro, Sobue Gen, Hasegawa Toshikazu, Ota Jun, Saitoe Minoru, Kadomatsu Kenji, Kida Satoshi, Manabe Toshiya, Tomita Taisuke, Iwata Atsushi, Murakami Ikuya, Tsutsui Ken-ichiro, Hanakawa Takashi, Hirai Hirokazu, Mima Tatsuya, Isomura Yoshikazu, Samejima Kazuyuki, Hoshi Eiji, Miyata Mariko, Yuzaki Michisuke, Tanaka Masaki, Fukata Masaki, Suzuki Kyoko, Kuba Hiroshi, Masu Masayuki, Kinoshita Makoto, Sugihara Izumi, Shirane Michiko, Yamamoto Nobuhiko, Nishijo Hisao, Nambu Atsushi, Takumi Toru, Yamashita Toshihide, Sakurai Takeshi, Tamamaki Nobuaki, Hata Yoshio, Harada Akihiro, Ozaki Norio, Sakai Katsuyuki, Kubo Yoshihiro, Nakazawa Takanobu, Tanaka Kenji, Takei Nobuyuki, Hitoshi Seiji, Takahiroa. Kato, Kato Fusao, Shirao Tomoaki, Taira Masato, Okano Hideyuki, Sekino Yuko, Okamoto Yasumasa, KOMATSU Hidehiko, Miyata Takaki, Takahashi Yoshiko, Nishida Shinya, Tominaga Makoto
  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2014
    TAKAHASHI RYOSUKE
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