大黒多希子 (Takiko Daikoku) - マイポータル

基本情報

所属: 金沢大学疾患モデル総合研究センター教授

J-GLOBAL ID: 201801000347444985
researchmap会員ID: B000303477

研究キーワード

研究分野

経歴

2021年4月 - 現在

金沢大学, 疾患モデル総合研究センター疾患モデル分野, 教授
2015年6月 - 2021年3月

金沢大学, 学際科学実験センター遺伝子改変動物分野, 教授
2011年9月 - 2015年6月

Cincinnati Children’s Hospital Medical Center, USA, Division of Reproductive Sciences, Research Associate Professor
2008年5月 - 2011年8月

Cincinnati Children’s Hospital Medical Center, USA, Division of Reproductive Sciences, Research Assistant Professor
2004年3月 - 2008年5月

Vanderbilt University Medical Center, USA, Department of Pediatrics, Research Assistant Professor
2002年7月 - 2004年2月

Vanderbilt University Medical Center, USA, Department of Pediatrics, Postdoctoral Fellow
2001年9月 - 2002年6月

University of Kansas Medical Center, USA, Department of Molecular and Integrative, Postdoctoral Fellow
2000年4月 - 2001年9月

University of Kansas Medical Center, USA, Department of Biochemistry, Postdoctoral Fellow

学歴

委員歴

主要な論文

Spheroid formation induces chemokine production in trophoblast-derived Swan71 cells.

Tatsuhito Kanda, Kyosuke Kagami, Takashi Iizuka, Haruki Kasama, Takeo Matsumoto, Yuya Sakai, Takuma Suzuki, Megumi Yamamoto, Ayumi Matsuoka, Rena Yamazaki …

American journal of reproductive immunology (New York, N.Y. : 1989) 90(2) e13752 2023年8月査読有り
Androgen promotes squamous differentiation of atypical cells in cervical intraepithelial neoplasia via an <scp>ELF3</scp>‐dependent pathway

Takeo Matsumoto, Takuma Suzuki, Mitsuhiro Nakamura, Megumi Yamamoto, Takashi Iizuka, Masanori Ono, Kyosuke Kagami, Haruki Kasama, Tatsuhito Kanda, Yuya Sakai …

Cancer Medicine 12(9) 10816-10828 2023年3月23日査読有り責任著者
<scp>FOXP4</scp> inhibits squamous differentiation of atypical cells in cervical intraepithelial neoplasia via an <scp>ELF3</scp>‐dependent pathway

Takeo Matsumoto, Takashi Iizuka, Mitsuhiro Nakamura, Takuma Suzuki, Megumi Yamamoto, Masanori Ono, Kyosuke Kagami, Haruki Kasama, Kousho Wakae, Masamichi Muramatsu …

Cancer Science 113(10) 3376-3389 2022年8月責任著者
Uterine Deletion of Bmal1 Impairs Placental Vascularization and Induces Intrauterine Fetal Death in Mice

Masanori Ono, Natsumi Toyoda, Kyosuke Kagami, Takashi Hosono, Takeo Matsumoto, Shin-ichi Horike, Rena Yamazaki, Mitsuhiro Nakamura, Yasunari Mizumoto, Tomoko Fujiwara …

International Journal of Molecular Sciences 23(14) 2022年7月査読有り責任著者
Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells.

Yuka Mise, Junzo Hamanishi, Takiko Daikoku, Shiro Takamatsu, Taito Miyamoto, Mana Taki, Koji Yamanoi, Ken Yamaguchi, Masayo Ukita, Naoki Horikawa …

Carcinogenesis 43(7) 647-658 2022年3月30日査読有り
A novel oral inhibitor for one-carbon metabolism and checkpoint kinase 1 inhibitor as a rational combination treatment for breast cancer.

Jin Lee, Xiaoxi Chen, Yuming Wang, Tatsunori Nishimura, Mengjiao Li, Satoko Ishikawa, Takiko Daikoku, Junya Kawai, Arinobu Tojo, Noriko Gotoh

Biochemical and biophysical research communications 584 7-14 2021年12月20日査読有り
Mucinous, endometrioid, and serous ovarian cancers with peritoneal dissemination are potent candidates for P-cadherin targeted therapy: a retrospective cohort study.

Kayo Kayahashi, Yasunari Mizumoto, Ayumi Matsuoka, Takeshi Obata, Junpei Iwadare, Mitsuhiro Nakamura, Takiko Daikoku, Hiroshi Fujiwara

BMC cancer 21(1) 32-32 2021年1月7日査読有り
Promoting Roles of Embryonic Signals in Embryo Implantation and Placentation in Cooperation with Endocrine and Immune Systems.

Hiroshi Fujiwara, Masanori Ono, Yukiyasu Sato, Kazuhiko Imakawa, Takashi Iizuka, Kyosuke Kagami, Tomoko Fujiwara, Akihito Horie, Hirohiko Tani, Akira Hattori …

International journal of molecular sciences 21(5) 2020年3月10日査読有り
The Association and Significance of p53 in Gynecologic Cancers: The Potential of Targeted Therapy.

Mitsuhiro Nakamura, Takeshi Obata, Takiko Daikoku, Hiroshi Fujiwara

International journal of molecular sciences 20(21) 2019年11月4日査読有り
IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma.

Satoshi Kofuji, Akiyoshi Hirayama, Alexander Otto Eberhardt, Risa Kawaguchi, Yuki Sugiura, Oltea Sampetrean, Yoshiki Ikeda, Mikako Warren, Naoya Sakamoto, Shuji Kitahara …

Nature cell biology 21(8) 1003-1014 2019年8月査読有り
Ovarian insufficiency and CTNNB1 mutations drive malignant transformation of endometrial hyperplasia with altered PTEN/PI3K activities.

Terakawa J, Serna VA, Taketo MM, Daikoku T, Suarez AA, Kurita T

Proceedings of the National Academy of Sciences of the United States of America 2019年2月査読有り
Novel strategy of ovarian cancer implantation: Pre-invasive growth of fibrin-anchored cells with neovascularization

Ayumi Matsuoka, Yasunari Mizumoto, Masanori Ono, Kyosuke Kagami, Takeshi Obata, Junpei Terakawa, Yoshiko Maida, Mitsuhiro Nakamura, Takiko Daikoku, Hiroshi Fujiwara

Cancer Science 110(8) 2658-2666 2019年査読有り
The uterine epithelial loss of Pten is inefficient to induce endometrial cancer with intact stromal Pten.

Liang X, Daikoku T, Terakawa J, Ogawa Y, Joshi AR, Ellenson LH, Sun X, Dey SK

PLoS genetics 14(8) e1007630 2018年8月査読有り筆頭著者
Crosstalk between PKCα and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium.

Hsu AH, Lum MA, Shim KS, Frederick PJ, Morrison CD, Chen B, Lele SM, Sheinin YM, Daikoku T, Dey SK …

Cell reports 24(3) 655-669 2018年7月査読有り
Factors Regulating Human Extravillous Trophoblast Invasion: Chemokine-peptidase and CD9-integrin Systems.

Hiroshi Fujiwara, Hisanori Matsumoto, Yukiyasu Sato, Akihito Horie, Masanori Ono, Mitsuhiro Nakamura, Yasunari Mizumoto, Kyosuke Kagami, Tomoko Fujiwara, Akira Hattori …

Current pharmaceutical biotechnology 19(10) 764-770 2018年査読有り
Dual expression of immunoreactive estrogen receptor β and p53 is a potential predictor of regional lymph node metastasis and postoperative recurrence in endometrial endometrioid carcinoma.

Obata T, Nakamura M, Mizumoto Y, Iizuka T, Ono M, Terakawa J, Daikoku T, Fujiwara H

PloS one 12(11) e0188641 2017年11月査読有り
Dual Positive Regulation of Embryo Implantation by Endocrine and Immune Systems - Step-by-Step Maternal Recognition of the Developing Embryo

Hiroshi Fujiwara, Yoshihiko Araki, Kazuhiko Imakawa, Shigeru Saito, Takiko Daikoku, Minoru Shigeta, Hideharu Kanzaki, Takahide Mori

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY 75(3) 281-289 2016年3月査読有り
The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.

Sumita K, Lo YH, Takeuchi K, Senda M, Kofuji S, Ikeda Y, Terakawa J, Sasaki M, Yoshino H, Majd N …

Molecular cell 61(2) 187-198 2016年1月査読有り
The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.

Kazutaka Sumita, Yu-Hua Lo, Koh Takeuchi, Miki Senda, Satoshi Kofuji, Yoshiki Ikeda, Jumpei Terakawa, Mika Sasaki, Hirofumi Yoshino, Nazanin Majd …

Mol. Cell 61(2) 187-198 2016年1月査読有り
Neutrophils Oppose Uterine Epithelial Carcinogenesis via Debridement of Hypoxic Tumor Cells

Adam Blaisdell, Amandine Crequer, Devin Columbus, Takiko Daikoku, Khush Mittal, Sudhansu K. Dey, Adrian Erlebacher

CANCER CELL 28(6) 785-799 2015年12月査読有り
SSK1, a novel GTP-dependent kinase, detects GTP levels and regulates tumorigenesis

Sumita K, Takeuchi K, Lo Y, Senda M, Kofuji S, Ikeda Y, Yoshino H, Sasaki M, Terakawa J, Daikoku T …

Molecular Biology of the Cell 26 2015年査読有り
Mammalian Target of Rapamycin Complex 1 and Cyclooxygenase 2 Pathways Cooperatively Exacerbate Endometrial Cancer

Takiko Daikoku, Jumpei Terakawa, Md M. Hossain, Mikihiro Yoshie, Monica Cappelletti, Peiying Yang, Lora H. Elenson, Sudhansu K. Dey

AMERICAN JOURNAL OF PATHOLOGY 184(9) 2390-2402 2014年9月査読有り筆頭著者責任著者
Lactoferrin-iCre: A New Mouse Line to Study Uterine Epithelial Gene Function

Takiko Daikoku, Yuya Ogawa, Jumpei Terakawa, Akiyo Ogawa, Tony DeFalco, Sudhansu K. Dey

ENDOCRINOLOGY 155(7) 2718-2724 2014年7月査読有り筆頭著者責任著者
Ovarian LGR5 is critical for successful pregnancy

Xiaofei Sun, Jumpei Terakawa, Hans Clevers, Nick Barker, Takiko Daikoku, Sudhansu K. Dey

FASEB JOURNAL 28(5) 2380-2389 2014年5月査読有り責任著者
A review of the potential utility of Mycophenolate Mofetil as a cancer therapeutic.

Majd N, Sumita K, Yoshino H, Chen D, Terakawa J, Daikoku T, Kofuji S, Curry R, Wise-Draper T, Warnick R …

Journal of Cancer Research ID 423401 2014年査読有り
CXCR2-Expressing Myeloid-Derived Suppressor Cells Are Essential to Promote Colitis-Associated Tumorigenesis

Hiroshi Katoh, Dingzhi Wang, Takiko Daikoku, Haiyan Sun, Sudhansu K. Dey, Raymond N. DuBois

CANCER CELL 24(5) 631-644 2013年11月査読有り
Conditional deletion of Tsc1 in the female reproductive tract impedes normal oviductal and uterine function by enhancing mTORC1 signaling in mice

Takiko Daikoku, Mikihiro Yoshie, Huirong Xie, Xiaofei Sun, Jeeyeon Cha, Lora Hedrick Ellenson, Sudhansu K. Dey

MOLECULAR HUMAN REPRODUCTION 19(7) 463-472 2013年7月査読有り筆頭著者責任著者
Cyclocreatine treatment improves cognition in mice with creatine transporter deficiency

Yuko Kurosawa, Ton J. DeGrauw, Diana M. Lindquist, Victor M. Blanco, Gail J. Pyne-Geithman, Takiko Daikoku, James B. Chambers, Stephen C. Benoit, Joseph F. Clark

JOURNAL OF CLINICAL INVESTIGATION 122(8) 2837-2846 2012年8月査読有り
Conditional Deletion of MSX Homeobox Genes in the Uterus Inhibits Blastocyst Implantation by Altering Uterine Receptivity

Takiko Daikoku, Jeeyeon Cha, Xiaofei Sun, Susanne Tranguch, Huirong Xie, Tomoko Fujita, Yasushi Hirota, John Lydon, Francesco DeMayo, Robert Maxson …

DEVELOPMENTAL CELL 21(6) 1014-1025 2011年12月査読有り筆頭著者
Heightened uterine mammalian target of rapamycin complex 1 (mTORC1) signaling provokes preterm birth in mice

Yasushi Hirota, Jeeyeon Cha, Mikihiro Yoshie, Takiko Daikoku, Sudhansu K. Dey

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108(44) 18073-18078 2011年11月査読有り
Cell-specific conditional deletion of Pten in the uterus results in differential phenotypes

Takiko Daikoku, Lindsey Jackson, Valerie Besnard, Jeffrey Whitsett, Lora Hedrick Ellenson, Sudhansu K. Dey

GYNECOLOGIC ONCOLOGY 122(2) 424-429 2011年8月査読有り筆頭著者責任著者
Uterine FK506-binding protein 52 (FKBP52)-peroxiredoxin-6 (PRDX6) signaling protects pregnancy from overt oxidative stress

Yasushi Hirota, Nuray Acar, Susanne Tranguch, Kristin E. Burnum, Huirong Xie, Ako Kodama, Yutaka Osuga, Ismail Ustunel, David B. Friedman, Richard M. Caprioli …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107(35) 15577-15582 2010年8月査読有り
Uterine-specific p53 deficiency confers premature uterine senescence and promotes preterm birth in mice

Yasushi Hirota, Takiko Daikoku, Susanne Tranguch, Huirong Xie, Heather B. Bradshaw, Sudhansu K. Dey

JOURNAL OF CLINICAL INVESTIGATION 120(3) 803-815 2010年3月査読有り
CYP1B1 expression in ovarian cancer in the laying hen Gallus domesticus

Yan Zhuge, Jo Ann J. Lagman, Kristine Ansenberger, Cassandra J. Mahon, Takiko Daikoku, Sudhansu K. Dey, Janice M. Bahr, Dale B. Hales

GYNECOLOGIC ONCOLOGY 112(1) 171-178 2009年1月査読有り
Two faces of PTEN

Takiko Daikoku, Sudhansu K. Dey

NATURE MEDICINE 14(11) 1192-1193 2008年11月査読有り筆頭著者
Conditional loss of uterine Pten unfailingly and rapidly induces endometrial cancer in mice

Takiko Daikoku, Yasushi Hirota, Susanne Tranguch, Ayesha R. Joshi, Francesco J. DeMayo, John P. Lydon, Lora H. Ellenson, Sudhansu K. Dey

CANCER RESEARCH 68(14) 5619-5627 2008年7月査読有り筆頭著者
MicroRNA regulation of cyclooxygenase-2 during embryo implantation

Anindita Chakrabarty, Susanne Tranguch, Takiko Daikoku, Kevin Jensen, Henry Furneaux, Sudhansu K. Dey

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104(38) 15144-15149 2007年9月査読有り
FKBP52 deficiency-conferred uterine progesterone resistance is genetic background and pregnancy stage specific

Susanne Tranguch, Haibin Wang, Takiko Daikoku, Huirong Xie, David F. Smith, Sudhansu K. Dey

JOURNAL OF CLINICAL INVESTIGATION 117(7) 1824-1834 2007年7月査読有り
Extracellular signal-regulated kinase is a target of cyclooxygenase-1-peroxisome proliferator-activated receptor-delta signaling in epithelial ovarian cancer

Takiko Daikoku, Susanne Tranguch, Anindita Chakrabarty, Dingzhi Wang, Dineo Khabele, Sandra Orsulic, Jason D. Morrow, Raymond N. DuBois, Sudhansu K. Dey

CANCER RESEARCH 67(11) 5285-5292 2007年6月査読有り筆頭著者
CXCL1 induced by prostaglandin E-2 promotes angiogenesis in colorectal cancer

DZ Wang, HB Wang, J Brown, T Daikoku, W Ning, Q Shi, A Richmond, R Strieter, SK Dey, RN DuBois

JOURNAL OF EXPERIMENTAL MEDICINE 203(4) 941-951 2006年4月査読有り
Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer

T Daikoku, S Tranguch, IN Trofimova, DM Dinulescu, T Jacks, AY Nikitin, DC Connony, SK Dey

CANCER RESEARCH 66(5) 2527-2531 2006年3月査読有り筆頭著者
Levels of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-alpha

T Otani, K Yamaguchi, E Scherl, BH Du, HH Tai, M Greifer, L Petrovic, T Daikoku, SK Dey, K Subbaramaiah …

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 290(2) G361-G368 2006年2月査読有り
Cochaperone immunophilin FKBP52 is critical to uterine receptivity for embryo implantation

S Tranguch, J Cheung-Flynn, T Daikoku, Prapapanich, V, MB Cox, HR Xie, HB Wang, SK Das, DF Smith, SK Dey

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(40) 14326-14331 2005年10月査読有り
Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer

T Daikoku, DZ Wang, S Tranguch, JD Morrow, S Orsulic, RN DuBois, SK Dey

CANCER RESEARCH 65(9) 3735-3744 2005年5月査読有り筆頭著者
Global gene expression analysis identifies molecular pathways distinguishing blastocyst dormancy and activation

T Hamatani, T Daikoku, HB Wang, H Matsumoto, MG Carter, MSH Ko, SK Dey

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(28) 10326-10331 2004年7月査読有り
Molecular cues to implantation

SK Dey, H Lim, SK Das, J Reese, BC Paria, T Daikoku, HB Wang

ENDOCRINE REVIEWS 25(3) 341-373 2004年6月査読有り
Expression of hypoxia-inducible factors in the peri-implantation mouse uterus is regulated in a cell-specific and ovarian steroid hormone-dependent manner - Evidence for differential function of HIFs during early pregnancy

T Daikoku, H Matsumoto, RA Gupta, SK Das, M Gassmann, RN Dubois, SK Dey

JOURNAL OF BIOLOGICAL CHEMISTRY 278(9) 7683-7691 2003年2月査読有り
Cyclooxygenase-2 differentially directs uterine angiogenesis during implantation in mice

H Matsumoto, WG Ma, T Daikoku, XM Zhao, BC Paria, SK Das, JM Trzaskos, SK Dey

JOURNAL OF BIOLOGICAL CHEMISTRY 277(32) 29260-29267 2002年8月査読有り
Dramatic enhancement of the specific expression of the heart-type fatty acid binding protein in rat brown adipose tissue by cold exposure.

Daikoku T, Shinohara Y, Shima A, Yamazaki N, Terada H

FEBS letters 410(2-3) 383-386 1997年6月査読有り筆頭著者

もっとみる

MISC

子宮がん発生を制御する分子機構の解明

大黒多希子, 寺川純平, 松岡歩, 水本泰成, 藤原浩

がんと代謝研究会プログラム&抄録集 8th 2022年
UTERINE-SPECIFIC BMAL1 DELETION DISRUPTS MATERNAL NEOVASCULARIZATION DURING DECIDUALIZATION/PLACENTATION AND LEADS TO MISCARRIAGE DEATH

Masanori Ono, Natsumi Toyoda, Takashi Hosono, Kyosuke Kagami, Jumpei Terakawa, Tomoko Fujiwara, Mieda Michihiro, Hitoshi Ando, Hiroshi Fujiwara, Takiko Daikoku

PLACENTA 114 141-142 2021年10月
子宮上皮Gp130は転写抑制因子Snail1の発現およびエストロゲン応答性の減弱を介してマウス胚着床を誘起する

並木貴文, 唐釜春実, 寺川純平, 大黒多希子, 影山敦子, 長谷川嘉則, 小原収, 伊藤潤哉, 柏崎直巳

日本絨毛性疾患研究会・日本胎盤学会学術集会プログラム・抄録集 39th-29th 2021年
マウスモデルを用いた子宮がん発生を制御する分子機構の解明

寺川純平, 井之上幸範, 松岡歩, 水本泰成, 藤原浩, 大黒多希子

日本生殖医学会雑誌 64(3) 110-110 2019年7月
A novel mouse model of endometrial cancer: epithelial specific Pten deletion with lactoferrin-iCre

Takiko Daikoku, Jumpei Terakawa, Sudhansu K. Dey

CANCER RESEARCH 75 2015年8月
DISCOVERY OF A p53-INDEPENDENT SUPPRESSOR OF SENESCENCE OF GLIOBLASTOMA MULTIFORME

Kazutaka Sumita, Mindy Davis, Rajan Pragani, Jumpei Terakawa, Takiko Daikoku, Nazanin Majd, Min Shen, Zhuyin Li, Xin Hu, Lewis Cantley …

NEURO-ONCOLOGY 16 2014年11月
Involvement of cAMP Signaling Mediators, Epac1, Epac2 and Rap1 in Decidualization of Rat Uterus

Mikihiro Yoshie, Kazuya Kusama, Kazuhiro Tamura, Takiko Daikoku, Tsutomu Takarada, Eiichi Tachikawa

ENDOCRINE REVIEWS 35(3) 2014年6月
Intersection of mTORC1 and COX2 pathways as potential therapeutic targets in a mouse model of endometrial cancer

Takiko Daikoku, Jumpei Terakawa, Sudhansu K. Dey

CANCER RESEARCH 73 2013年10月
Dominant expression of NAD(+)-dependent isocitrate dehydrogenase in brown adipose tissue

K Kajimoto, T Daikoku, N Yamazaki, Y Shinohara, H Terada

MOLECULAR BIOLOGY OF THE CELL 13 130A-130A 2002年11月
Differences in the expression of proteins in white and brown adipose tissues

A Shima, K Kajimoto, T Daikoku, Y Shinohara, N Yamazaki, H Terada

MOLECULAR BIOLOGY OF THE CELL 12 97A-98A 2001年11月

書籍等出版物

HORMONE FRONTIER IN GYNECOLOGY

大黒多希子 (担当:分担執筆, 範囲:グラビア：目で見る遺伝子改変マウスによる生殖機能解析ー子宮時計遺伝子機能の解析ー)

2023年3月
ヒトゲノム事典

井ノ上, 逸朗, 今西, 規, 河村, 正二, 斎藤, 成也, 颯田, 葉子, 田嶋, 敦 (担当:分担執筆, 範囲:25.2 受精卵着床にかかわる遺伝子)

一色出版 2021年11月 (ISBN: 9784910389127)

主要な講演・口頭発表等

Bmal1時計遺伝子欠損マウスにおける胎盤形成不全

大黒多希子

第62回日本先天異常学会学術集会 2022年7月31日招待有り
子宮がん発生を制御する分子機構の解明

大黒多希子, 寺川純平, 松岡歩, 水本泰成, 藤原浩

第8回がんと代謝研究会 in佐渡 2022年7月20日
マウスモデルを用いた子宮体癌発症・進展に対する女性ホルモンの影響についての解析

大黒多希子

第26回日本生殖内分泌学会学術集会 2022年1月18日招待有り
マウスモデルを用いた子宮がん発生を制御する分子機構の解明

寺川純平, 井之上幸範, 松岡歩, 水本泰成, 藤原浩, 大黒多希子

日本生殖医学会雑誌 2019年7月 (一社)日本生殖医学会
マウスモデルを用いた子宮疾患の解析

大黒多希子

第５８回日本組織細胞科学会総会・学術総会 2017年9月24日招待有り
マウスモデルからみる子宮疾患

大黒多希子

第５３回北陸生殖医学会学術講演会 2017年6月11日招待有り
マウスモデルを用いた子宮疾患の解析

第６２回日本病理学会秋季特別総会 2016年11月11日招待有り
Protein kinase C alpha suppresses AKT activation in endometrial cancer

Alice H. Hsu, Kathryn J. Curry, Kang-Sup Shim, Peter Frederick, Carl D. Morrison, Baojiang Chen, Subodh M. Lele, Takiko Daikoku, Sudhansu K. Dey, Gustavo Leone, Adrian R. Black, Jennifer D. Black

CANCER RESEARCH 2016年7月 AMER ASSOC CANCER RESEARCH
Protein kinase C alpha (PKC alpha) regulates PI3K/AKT signaling in endometrial cancer

Alice H. Hsu, Kathryn J. Curry, Kang-Sup Shim, Peter Frederick, Carl Morrison, Baojing Chen, Subodh M. Lele, Takiko Daikoku, Sudhansu K. Dey, Gustavo Leone, Adrian R. Black, Jennifer D. Black

CANCER RESEARCH 2015年8月 AMER ASSOC CANCER RESEARCH
A novel mouse model of endometrial cancer: epithelial specific Pten deletion with lactoferrin-iCre

Takiko Daikoku, Jumpei Terakawa, Sudhansu K. Dey

CANCER RESEARCH 2015年8月 AMER ASSOC CANCER RESEARCH
DISCOVERY OF A p53-INDEPENDENT SUPPRESSOR OF SENESCENCE OF GLIOBLASTOMA MULTIFORME

Kazutaka Sumita, Mindy Davis, Rajan Pragani, Jumpei Terakawa, Takiko Daikoku, Nazanin Majd, Min Shen, Zhuyin Li, Xin Hu, Lewis Cantley, Matthew Boxer, Anton Simeonov, Atsuo Sasaki

NEURO-ONCOLOGY 2014年11月 OXFORD UNIV PRESS INC
Neutrophil recruitment into premalignant lesions differentially influences tumor growth versus progression.

Adam Blaisdell, Takiko Daikoku, Chin Siean Tay, Sudhansu Dey, Adrian Erlebacher

JOURNAL OF IMMUNOLOGY 2014年5月 AMER ASSOC IMMUNOLOGISTS
GTPエネルギーを感知するキナーゼの同定と癌における役割

佐々木敦朗, 竹内恒, 壽美田一貴, LO Yu‐Hua, 千田美紀, 寺川純平, 大黒多希子, CANTLEY Lewis, 千田俊哉

日本分子生物学会年会プログラム・要旨集(Web) 2014年
Intersection of mTORC1 and COX2 pathways as potential therapeutic targets in a mouse model of endometrial cancer

Takiko Daikoku, Jumpei Terakawa, Sudhansu K. Dey

CANCER RESEARCH 2013年10月 AMER ASSOC CANCER RESEARCH
Increased Mammalian Target of Rapamycin Complex-1 (mTORC1) Signaling Is a Major Contributor to Preterm Birth

Jeeyeon M. Cha, Yasushi Hirota, Takiko Daikoku, Sudhansu K. Dey

REPRODUCTIVE SCIENCES 2012年3月 SAGE PUBLICATIONS INC
Potential Combination Therapy to Combat Endometrial Cancer

Takiko Daikoku, Lindsey Jackson, Sudhansu K. Dey

CANCER RESEARCH 2011年4月 AMER ASSOC CANCER RESEARCH
COX-1-PPAR delta signaling axis in epithelial ovarian tumor.

T Daikoku, DZ Wang, S Orsulic, RN DuBois, SK Dey

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 2005年11月 AMER ASSOC CANCER RESEARCH