CHAO-YUAN TSAI

Profile Information

Degree: Ph.D.(台湾國立成功大學)

J-GLOBAL ID: 201801009547629499
researchmap Member ID: B000309407

Research Areas

Awards

Dec, 2021

Best Presentation Award, Differential roles of RUBCN isoforms in the fate decision of germinal center B cells, Japanese Society for Immunology

CHAO-YUAN TSAI

Papers

Multiple tolerance checkpoints restrain affinity maturation of B cells expressing the germline precursor of a lupus patient-derived anti-dsDNA antibody in knock-in mice.

Marwa Ali El Hussien, Chao-Yuan Tsai, Yuhkoh Satouh, Daisuke Motooka, Daisuke Okuzaki, Masahito Ikawa, Hitoshi Kikutani, Shuhei Sakakibara

International immunology, 34(4) 207-223, Dec 1, 2021 Peer-reviewed
Starvation-induced autophagy via calcium-dependent TFEB dephosphorylation is suppressed by Shigyakusan

Sumiko Ikari, Shiou-Ling Lu, Feike Hao, Kenta Imai, Yasuhiro Araki, Yo-hei Yamamoto, Chao-Yuan Tsai, Yumi Nishiyama, Nobukazu Shitan, Tamotsu Yoshimori …

PLOS ONE, 15(3) e0230156-e0230156, Mar 5, 2020 Peer-reviewed
Self-reactive and polyreactive B cells are generated and selected in the germinal center during γ-herpesvirus infection.

Shuhei Sakakibara, Teruhito Yasui, Hideyuki Jinzai, Kristy O'donnell, Chao-Yuan Tsai, Takeharu Minamitani, Kazuya Takeda, Gabrielle T Belz, David M Tarlinton, Hitoshi Kikutani

International immunology, 32(1) 27-38, Jan 9, 2020 Peer-reviewed
Bystander inhibition of humoral immune responses by Epstein-Barr virus LMP1

Tsai CY, Sakakibara S, Yasui T, Minamitani T, Okuzaki D, Kikutani H

International Immunology, 30(12) 579-590, Dec, 2018 Peer-reviewed
Bystander inhibition of humoral immune responses by Epstein-Barr virus LMP1

Chao-Yuan Tsai, Shuhei Sakakibara, Teruhito Yasui, Takeharu Minamitani, Daisuke Okuzaki, Hitoshi Kikutani

International immunology, 30(12) 579-590, Nov 14, 2018 Peer-reviewedLead author
Mouse model of Epstein-Barr virus LMP1-and LMP2A-driven germinal center B-cell lymphoproliferative disease

Takeharu Minamitani, Yijie Ma, Hufeng Zhou, Hiroshi Kida, Chao-Yuan Tsai, Masanori Obana, Daisuke Okuzaki, Yasushi Fujio, Atsushi Kumanogoh, Bo Zhao …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(18) 4751-4756, May, 2017 Peer-reviewed
Akt/mTOR axis in antigen-committed B cells regulates IgA+ plasma cell differentiation

Takeharu Minamitani, Shuhei Sakakibara, Chao-Yuan Tsai, Hitoshi Kikutani, Teruhito Yasui

Nov, 2015 Peer-reviewed
Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A

Takeharu Minamitani, Teruhito Yasui, Yijie Ma, Hufeng Zhou, Daisuke Okuzaki, Chiau-Yuang Tsai, Shuhei Sakakibara, Benjamin E. Gewurz, Elliott Kieff, Hitoshi Kikutani

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(37) 11612-11617, Sep, 2015 Peer-reviewed
Kallistatin modulates immune cells and confers anti-inflammatory response to protect mice from group A streptococcal infection

Lu SL, Tsai CY, Luo YH, Kuo CF, Lin WC, Chang YT, Wu JJ, Chuang WJ, Liu CC, Chao L …

Antimicrobial Agents and Chemotherapy, 57(11) 5366-5372, Nov, 2013 Peer-reviewed
Multivalent structure of galectin-1-nanogold complex serves as potential therapeutics for rheumatoid arthritis by enhancing receptor clustering

Huang YJ, Shiau AL, Chen SY, Chen YL, Wang CR, Tsai CY, Chang MY, Li YT, Leu CH, Wu CL

eCells & Materials, 23 170-181, Mar, 2012
Size-Dependent Attenuation of TLR9 Signaling by Gold Nanoparticles in Macrophages

Chiau-Yuang Tsai, Shiou-Ling Lu, Chia-Wen Hu, Chen-Sheng Yeh, Gwo-Bin Lee, Huan-Yao Lei

JOURNAL OF IMMUNOLOGY, 188(1) 68-76, Jan, 2012 Peer-reviewedLead author
Enhancing Transversal Relaxation for Magnetite Nanoparticles in MR Imaging Using Gd3+-Chelated Mesoporous Silica Shells

Chih-Chia Huang, Chiau-Yuang Tsai, Hwo-Shuenn Sheu, Kuei-Yi Chuang, Chiu-Hun Su, U-Ser Jeng, Fong-Yu Cheng, Chia-Hao Su, Huan-Yao Lei, Chen-Sheng Yeh

ACS NANO, 5(5) 3905-3916, May, 2011 Peer-reviewedLead author
Size-control synthesis of structure deficient truncated octahedral Fe3-delta O4 nanoparticles: high magnetization magnetites as effective hepatic contrast agents

Chih-Chia Huang, Kuei-Yi Chuang, Chen-Pin Chou, Ming-Ting Wu, Hwo-Shuenn Sheu, Dar-Bin Shieh, Chiau-Yuang Tsai, Chia-Hao Su, Huan-Yao Lei, Chen-Sheng Yeh

JOURNAL OF MATERIALS CHEMISTRY, 21(20) 7472-7479, 2011 Peer-reviewed
Methotrexate conjugated to gold nanoparticles inhibits tumor growth in a syngeneic lung tumor model

Yu-Hung Chen, Chiau-Yuang Tsai, Pon-Yu Huang, Meng-Ya Chang, Pai-Chiao Cheng, Chen-Hsi Chou, Dong-Hwang Chen, Chrong-Reen Wang, Ai-Li Shiau, Chao-Liang Wu

MOLECULAR PHARMACEUTICS, 4(5) 713-722, Sep, 2007 Peer-reviewed
Amelioration of collagen-induced arthritis in rats by nanogold

Chiau-Yuang Tsai, Ai-Li Shiau, Shih-Yao Chen, Yu-Hung Chen, Pai-Chiao Cheng, Meng-Ya Chang, Dong-Hwang Chen, Chen-Hsi Chou, Chrong-Reen Wang, Chao-Liang Wu

ARTHRITIS AND RHEUMATISM, 56(2) 544-554, Feb, 2007 Peer-reviewedLead author
Aqueous dispersions of magnetite nanoparticles with NH3+ surfaces for magnetic manipulations of biomolecules and MRI contrast agents

DB Shieh, FY Cheng, CH Su, CS Yeh, MT Wu, YN Wu, CY Tsai, CL Wu, DH Chen, CH Chou

BIOMATERIALS, 26(34) 7183-7191, Dec, 2005 Peer-reviewed
Characterization of aqueous dispersions of Fe3O4 nanoparticles and their biomedical applications

FY Cheng, CH Su, YS Yang, CS Yeh, CY Tsai, CL Wu, MT Wu, DB Shieh

BIOMATERIALS, 26(7) 729-738, Mar, 2005 Peer-reviewed
A biological strategy for fabrication of Au/EGFP nanoparticle conjugates retaining bioactivity

TSAI CY

Nano Lett, 6(7) 1209-1212, May, 2004 Peer-reviewedLead author
A simple selection system for construction of recombinant gD-negative pseudorabies virus as a vaccine vector

AL Shiau, CW Liu, SY Wang, CY Tsai, CL Wu

VACCINE, 20(7-8) 1186-1195, Jan, 2002 Peer-reviewed

Professional Memberships

日本免疫学会 - 特定非営利活動法人日本免疫学会

Research Projects

The role of B cell-derived secretory autophagosome-like vesicles in immune regulation

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022

TSAI CHAOYUAN

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